Dilettante Fascination

Main themes of this blog: ANIME and SCIENCE. Although I like plenty of things which may show up from time to time. Like Doctor Who. Or Sherlock. Or Supernatural. Or Steins;Gate. Or Persona 3/4.
Peeps I Like

Are you telling me the TARDIS is going to have the same crack and the same desktop theme until the very end?

Other things I noticed:

  • Out of all the regenerations glimpsed on-screen, the Tenth Doctor never ran by. EDIT: Never mind. Ten’s in a little corner, with Clara watching over him in The Library. Hard to catch, that one.
  • Clara explicitly calls the Doctor “The Eleventh Doctor”. No one’s ever explicitly referred to the Doctor by number before. Better yet, he neither accepts nor denies it.
  • Being integrated throughout the entirety of his timestream, Clara must have encountered every Doctor—past, present, and future. But she only counted 11 of them, as well as John Hurt’s “denounced” Doctor. So is 12 lives the canon then? Better yet, is 11 the end of the line?
  • The Eleventh Doctor seems well aware of John Hurt’s “not”-Doctor—which places him sometime in his past, and not a future unknown regeneration. He’s either A) Before the First Doctor, before he took on the title or, the more popular theory B) Somewhere after Classic Who and before New Who…probably the one who ended the Time War.

Bonus thoughts: Clara was born to save the Doctor. Does she necessarily have to look like Clara though? My theory: Clara is every companion who ever was and ever will be.

Hey, why not.

PLEASE

(via doctorwho)

the-whisper-men:

at this exact moment, I lost my wits.

I died and I wasn’t even a minute in.

Babelcolour does better colorization tho.

(via doctorwho)

Doctor who?

(via doctorwho)

mucholderthen:

SCIENTIFIC ILLUSTRATION:  Nucleosome
The Mediterranean Institute for Life Sciences
Split, Croatia

High resolution ray-traced model of a nucleosome, isolated on black.

A nucleosome is the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around four histone protein cores.  This structure is often compared to thread wrapped around a spool.

Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it.  In mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter.  

Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression.

(Nucleosome - Wikipedia)

When it comes to replication, cells must produce more histones in order to compact the newly synthesized DNA.

When it comes to transcription, however, they’re a bit of a pain because they need to be removed or displaced in order to expose transcriptional factor binding sites. How does a cell do this? Well, transcription factors can recruit things like histone acetyltransferases to acetylate certain basic residues of the nucleosome; this weakens the interaction between the negatively charged DNA and the relatively positive nucleosome.

Cancerous cells like to recruit “activators” such as histone acetyltransferases in order to upregulate their transcription and, subsequently, protein production.

(via molecularlifesciences)

anime-backgrounds:

The Wolf Children Ame and Yuki. Directed by Mamoru Hosoda. Created by Studio Chizu and Madhouse.

butitsmorefunthatway:

it’s too cold outside

image

for angels to fly

It’s raining meOH GOD THIS ISN’T WHAT I ASKED FOR

(via dizzy-up-thegrl)

155,348 plays

doctorwho:

souffleguy:

The Doctor’s name from NAME OF THE DOCTOR LEAKED AUDIO ***SPOILERS***

Guise. We’re so disappointed. You had one job. ONE JOB.

I know what those jumbled words are. It’s the first part of the Joshiraku ED.

…why do I know these things.

Atoms aren’t just small: they’re really really small.
10^23 is an astonishingly large number. The number of grains of sand in all the beaches in the world is around 10^18. The number of stars in our galaxy is about 10^11. The number of stars in the entire visible Universe is probably around 10^22. And yet the
number of water molecules in a cup of tea is more than 10^23.
David Tong - Lecturer in statistical physics - University of Cambridge (via thecraftychemist)

(via centralscience)

jtotheizzoe:

Lightning Launch

Speaking of awesome lightning, did you know that Apollo 12’s Saturn V was struck by lightning less than a minute after launch? The bolt threw the navigation computer into chaos and then traveled down the energized exhaust plume.

Read about the white-knuckled minutes, the near-abort and controlled self-destruct that almost happened. Until a young  flight controller suggested they flip “SCE to AUX”.

(via Universe Today)

One of the earliest success stories of “steely-eyed missile man” John Aaron. He also had quite the role in bringing Apollo 13 back to Earth, devising the boot up sequence for the powered down Command Module for reentry. 

If you’ve watched Apollo 13, you probably remember that young fellow with the glasses. Huh. It’s been a while since I’ve watched it, actually. I should get around to it some time.