Are you telling me the TARDIS is going to have the same crack and the same desktop theme until the very end?
Other things I noticed:
Bonus thoughts: Clara was born to save the Doctor. Does she necessarily have to look like Clara though? My theory: Clara is every companion who ever was and ever will be.
Hey, why not.
PLEASE
(via doctorwho)
at this exact moment, I lost my wits.
I died and I wasn’t even a minute in.
…Babelcolour does better colorization tho.
(via doctorwho)
Doctor who?
(via doctorwho)
SCIENTIFIC ILLUSTRATION: Nucleosome
The Mediterranean Institute for Life Sciences
Split, CroatiaHigh resolution ray-traced model of a nucleosome, isolated on black.
A nucleosome is the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around four histone protein cores. This structure is often compared to thread wrapped around a spool.
Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it. In mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter.
Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression.
When it comes to replication, cells must produce more histones in order to compact the newly synthesized DNA.
When it comes to transcription, however, they’re a bit of a pain because they need to be removed or displaced in order to expose transcriptional factor binding sites. How does a cell do this? Well, transcription factors can recruit things like histone acetyltransferases to acetylate certain basic residues of the nucleosome; this weakens the interaction between the negatively charged DNA and the relatively positive nucleosome.
Cancerous cells like to recruit “activators” such as histone acetyltransferases in order to upregulate their transcription and, subsequently, protein production.
(via molecularlifesciences)
The Wolf Children Ame and Yuki. Directed by Mamoru Hosoda. Created by Studio Chizu and Madhouse.
it’s too cold outside
for angels to fly
It’s raining meOH GOD THIS ISN’T WHAT I ASKED FOR
(via dizzy-up-thegrl)
The Doctor’s name from NAME OF THE DOCTOR LEAKED AUDIO ***SPOILERS***
Guise. We’re so disappointed. You had one job. ONE JOB.
I know what those jumbled words are. It’s the first part of the Joshiraku ED.
…why do I know these things.
(via centralscience)
Lightning Launch
Speaking of awesome lightning, did you know that Apollo 12’s Saturn V was struck by lightning less than a minute after launch? The bolt threw the navigation computer into chaos and then traveled down the energized exhaust plume.
Read about the white-knuckled minutes, the near-abort and controlled self-destruct that almost happened. Until a young flight controller suggested they flip “SCE to AUX”.
(via Universe Today)
One of the earliest success stories of “steely-eyed missile man” John Aaron. He also had quite the role in bringing Apollo 13 back to Earth, devising the boot up sequence for the powered down Command Module for reentry.
If you’ve watched Apollo 13, you probably remember that young fellow with the glasses. Huh. It’s been a while since I’ve watched it, actually. I should get around to it some time.